BAIT
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
GO Process (6)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
LPIN2
lipin 2
GO Process (11)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- cellular lipid metabolic process [TAS]
- dephosphorylation [IBA, ISS]
- fatty acid catabolic process [IBA]
- glycerophospholipid biosynthetic process [TAS]
- lipid metabolic process [ISS]
- phosphatidylcholine biosynthetic process [TAS]
- phosphatidylethanolamine biosynthetic process [TAS]
- phospholipid metabolic process [TAS]
- positive regulation of transcription from RNA polymerase II promoter [IBA, ISS]
- small molecule metabolic process [TAS]
- triglyceride biosynthetic process [IBA, TAS]
Gene Ontology Molecular Function
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Pulse-SILAC and interactomics reveal distinct DDB1-CUL4 associated factors (DCAFs), cellular functions, and protein substrates.
Cullin-RING finger ligases (CRLs) represent the largest family of ubiquitin ligases. They are responsible for the ubiquitination of ?20% of cellular proteins degraded through the proteasome, by catalyzing the transfer of E2-loaded ubiquitin to a substrate. Seven Cullins are described in vertebrates. Among them, CUL4 associates with DDB1 to form the CUL4-DDB1 ubiquitin ligase complex, which is involved in protein ... [more]
Mol Cell Proteomics Sep. 07, 2023; ();100644 [Pubmed: 37689310]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID