BAIT

ACE2

ACEH, UNQ868/PRO1885
angiotensin I converting enzyme 2
Homo sapiens
PREY

SCARF2

NSR1, SREC-II, SREC2, SRECRP-1, VDEGS
scavenger receptor class F, member 2
GO Process (0)
GO Function (1)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Proximity Label-MS

An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.

Publication

High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.

Datta S, Chen DY, Tavares AH, Reyes-Robles T, Ryu KA, Khan N, Bechtel TJ, Bertoch JM, White CH, Hazuda DJ, Vora KA, Hett EC, Fadeyi OO, Oslund RC, Emili A, Saeed M

Identifying virus-host interactions on the cell surface can improve our understanding of viral entry and pathogenesis. SARS-CoV-2, the causative agent of the COVID-19 disease, uses ACE2 as a receptor to enter cells. Yet the full repertoire of cell surface proteins that contribute to viral entry is unknown. We developed a photocatalyst-based viral-host protein microenvironment mapping platform (ViraMap) to probe the ... [more]

Cell Chem Biol Jul. 17, 2023; (); [Pubmed: 37499664]

Throughput

  • High Throughput

Additional Notes

  • Enriched hits were identified with significant enrichment (log2FC greater than or equal to 1.5 and -log10p value of greater than or equal to 2 over control) and a SAINT BFDR of less than or equal to 0.01.
  • Photocatalyst-based microenvironment mapping platform.

Curated By

  • BioGRID