BAIT

LINC00632

RP1-177G6.2
long intergenic non-protein coding RNA 632
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

PGRMC1

HPR6.6, MPR
progesterone receptor membrane component 1
GO Process (0)
GO Function (2)
GO Component (4)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Protein-RNA

An interaction is detected between and protein and an RNA in vitro.

Publication

A novel lncRNA MDHDH suppresses glioblastoma multiforme by acting as a scaffold for MDH2 and PSMA1 to regulate NAD+ metabolism and autophagy.

He D, Xin T, Pang B, Sun J, Liu ZH, Qin Z, Ji XS, Yang F, Wei YB, Wang ZX, Gao JJ, Pang Q, Liu Q

To identify potential targets related to nicotinamide adenine dinucleotide (NAD+) metabolism in gliomas, we used RNA immunoprecipitation to identify a novel long noncoding RNA renamed malate dehydrogenase degradation helper (MDHDH) (NONCODE annotation ID: NONHSAT138800.2, NCBI Reference Sequence: NR_028345), which bound to MDH2 (malate dehydrogenase 2), that is downregulated in glioblastoma multiforme (GBM) and associated with metabolic regulation. However, its underlying ... [more]

J Exp Clin Cancer Res Dec. 17, 2022; 41(1);349 [Pubmed: 36527092]

Throughput

  • High Throughput

Curated By

  • BioGRID