Publication

Transportin 1 is a major nuclear import receptor of the nitric oxide synthase interacting protein.

Poerschke M, Rodriguez-Gonzalez I, Parfentev I, Urlaub H, Kehlenbach RH

The nitric oxide synthase interacting protein (NOSIP), an E3-ubiquitin ligase, is involved in various processes like neuronal development, craniofacial development, granulopoiesis, mitogenic signaling, apoptosis, and cell proliferation. The best-characterized function of NOSIP is the regulation of endothelial nitric oxide synthase activity by translocating the membrane-bound enzyme to the cytoskeleton, specifically in the G2 phase of the cell cycle. For this, ... [more]

Throughput

• Low Throughput

Curated By

• BioGRID