BAIT
NOSIP
CGI-25
nitric oxide synthase interacting protein
GO Process (5)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
IPO5
IMB3, KPNB3, Pse1, RANBP5, imp5, RP11-72J7.1
importin 5
GO Process (5)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Transportin 1 is a major nuclear import receptor of the nitric oxide synthase interacting protein.
The nitric oxide synthase interacting protein (NOSIP), an E3-ubiquitin ligase, is involved in various processes like neuronal development, craniofacial development, granulopoiesis, mitogenic signaling, apoptosis, and cell proliferation. The best-characterized function of NOSIP is the regulation of endothelial nitric oxide synthase activity by translocating the membrane-bound enzyme to the cytoskeleton, specifically in the G2 phase of the cell cycle. For this, ... [more]
J Biol Chem Mar. 01, 2023; 299(3);102932 [Pubmed: 36690276]
Throughput
- Low Throughput
Curated By
- BioGRID