BAIT

TAX1BP1

CALCOCO3, T6BP, TXBP151, PRO0105
Tax1 (human T-cell leukemia virus type I) binding protein 1
Autophagy Project
UPS Project
GO Process (3)
GO Function (2)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

UBA1

A1S9, A1S9T, A1ST, AMCX1, CFAP124, GXP1, POC20, SMAX2, UBA1A, UBE1, UBE1X, CTD-2522E6.1
ubiquitin-like modifier activating enzyme 1
UPS Project
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

TAX1BP1 protects against myocardial infarction-associated cardiac anomalies through inhibition of inflammasomes in a RNF34/MAVS/NLRP3-dependent manner.

Xu H, Yu W, Sun S, Li C, Ren J, Zhang Y

Acute myocardial infarction (MI), one of the most common cardiovascular emergencies, is a leading cause of morbidity and mortality. Ample evidence has revealed an essential role for inflammasome activation and autophagy in the pathogenesis of acute MI. Tax1-binding protein 1 (TAX1BP1), an adaptor molecule involved in termination of proinflammatory signaling, serves as an important selective autophagy adaptor, but its role ... [more]

Sci Bull (Beijing) Aug. 30, 2021; 66(16);1669-1683 [Pubmed: 36654301]

Throughput

  • Low Throughput

Curated By

  • BioGRID