BAIT
RNF207
C1orf188
ring finger protein 207
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
MYH10
MCH-B, NMMHC-B, SMemb
myosin, heavy chain 10, non-muscle
GO Process (28)
GO Function (6)
GO Component (21)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- actin cytoskeleton organization [ISO]
- actin filament-based movement [ISO]
- actomyosin structure organization [ISO]
- adult heart development [ISO]
- axon guidance [ISO]
- axonogenesis [ISO]
- brain development [ISO]
- cardiac myofibril assembly [ISO]
- cell proliferation [ISO]
- cellular component movement [NAS]
- cerebellar Purkinje cell layer development [ISO]
- exocytosis [ISO]
- fourth ventricle development [ISO]
- in utero embryonic development [ISO]
- lateral ventricle development [ISO]
- mitotic cytokinesis [ISO]
- myofibril assembly [ISO]
- neuromuscular process controlling balance [ISO]
- neuron migration [ISO]
- neuron projection development [ISO]
- nuclear migration [ISO]
- plasma membrane repair [ISO]
- regulation of cell shape [ISO]
- retina development in camera-type eye [ISO]
- substrate-dependent cell migration, cell extension [ISO]
- third ventricle development [ISO]
- ventricular cardiac muscle cell development [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [ISO]
- actomyosin [ISO]
- axon [ISO]
- cell cortex [ISO]
- cleavage furrow [ISO]
- cytoplasm [ISO]
- dendritic spine [ISO]
- extracellular vesicular exosome [ISO]
- growth cone [ISO]
- midbody [ISO]
- mitochondrion [ISO]
- myosin II complex [ISO]
- myosin II filament [ISO]
- myosin complex [ISO]
- neuromuscular junction [ISO]
- neuron projection [ISO]
- neuronal cell body [ISO]
- nucleus [ISO]
- plasma membrane [ISO]
- spindle [ISO]
- stress fiber [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1.
The heart undergoes pathological remodelling, featured by the hypertrophic growth of cardiomyocytes and increased cardiac fibrosis, under biomechanical stress such as haemodynamic overload. Ring Finger Protein 207 (RNF207) is an E3 ubiquitin ligase that is predominantly expressed in the heart, but its function remains elusive. In this study, we aimed to explore the role of RNF207 in the development of ... [more]
Cardiovasc Res Mar. 17, 2023; 119(1);183-194 [Pubmed: 35352799]
Throughput
- High Throughput
Curated By
- BioGRID