BAIT
RNF207
C1orf188
ring finger protein 207
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
MYH7
Myhcb
myosin, heavy chain 7, cardiac muscle, beta
GO Process (10)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- ATP catabolic process [IMP, ISO]
- adult heart development [ISO]
- muscle contraction [IMP, ISO]
- muscle filament sliding [ISO]
- regulation of heart rate [ISO]
- regulation of the force of heart contraction [ISO]
- response to reactive oxygen species [IEP]
- striated muscle contraction [ISO]
- transition between fast and slow fiber [ISO]
- ventricular cardiac muscle tissue morphogenesis [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1.
The heart undergoes pathological remodelling, featured by the hypertrophic growth of cardiomyocytes and increased cardiac fibrosis, under biomechanical stress such as haemodynamic overload. Ring Finger Protein 207 (RNF207) is an E3 ubiquitin ligase that is predominantly expressed in the heart, but its function remains elusive. In this study, we aimed to explore the role of RNF207 in the development of ... [more]
Cardiovasc Res Mar. 17, 2023; 119(1);183-194 [Pubmed: 35352799]
Throughput
- High Throughput
Curated By
- BioGRID