BAIT
RNF207
C1orf188
ring finger protein 207
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
VIM
vimentin
GO Process (21)
GO Function (12)
GO Component (16)
Gene Ontology Biological Process
- Bergmann glial cell differentiation [ISO]
- SMAD protein signal transduction [ISO]
- aging [IEP]
- astrocyte development [ISO]
- cellular response to fibroblast growth factor stimulus [IEP]
- decidualization [IEP]
- fat cell differentiation [IEP]
- intermediate filament organization [ISO]
- intermediate filament-based process [ISO]
- lens fiber cell development [ISO]
- negative regulation of neuron projection development [ISO]
- positive regulation of gene expression [ISO]
- positive regulation of glial cell proliferation [IMP]
- regulation of Schwann cell migration [IDA]
- regulation of axonogenesis [IDA]
- response to estradiol [IEP]
- response to radiation [IEP]
- response to selenium ion [IEP]
- response to vitamin D [IEP]
- response to zinc ion [IEP]
- skeletal muscle tissue regeneration [IEP]
Gene Ontology Molecular Function- double-stranded RNA binding [ISO]
- glycoprotein binding [ISO]
- identical protein binding [ISO]
- kinase binding [IPI]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- protein phosphatase 2A binding [IDA]
- scaffold protein binding [ISO]
- structural constituent of cytoskeleton [ISO, ISS]
- structural constituent of eye lens [ISO]
- structural molecule activity [ISO, TAS]
- double-stranded RNA binding [ISO]
- glycoprotein binding [ISO]
- identical protein binding [ISO]
- kinase binding [IPI]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- protein phosphatase 2A binding [IDA]
- scaffold protein binding [ISO]
- structural constituent of cytoskeleton [ISO, ISS]
- structural constituent of eye lens [ISO]
- structural molecule activity [ISO, TAS]
Gene Ontology Cellular Component
- axon [IDA]
- cell body [IDA]
- cell leading edge [ISO]
- cell projection [IDA, ISO]
- cytoplasm [IDA, ISO, ISS]
- cytoskeleton [IDA, ISO]
- cytosol [IDA, ISO]
- extracellular vesicular exosome [ISO]
- focal adhesion [ISO]
- intermediate filament [ISO, ISS]
- intermediate filament cytoskeleton [ISO]
- neuron projection [ISO]
- perinuclear region of cytoplasm [IDA]
- peroxisome [ISO]
- plasma membrane [ISO]
- type III intermediate filament [TAS]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1.
The heart undergoes pathological remodelling, featured by the hypertrophic growth of cardiomyocytes and increased cardiac fibrosis, under biomechanical stress such as haemodynamic overload. Ring Finger Protein 207 (RNF207) is an E3 ubiquitin ligase that is predominantly expressed in the heart, but its function remains elusive. In this study, we aimed to explore the role of RNF207 in the development of ... [more]
Cardiovasc Res Mar. 17, 2023; 119(1);183-194 [Pubmed: 35352799]
Throughput
- High Throughput
Curated By
- BioGRID