BAIT
RNF207
C1orf188
ring finger protein 207
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
MYO1C
Myr2
myosin IC
GO Process (9)
GO Function (3)
GO Component (16)
Gene Ontology Biological Process
- ATP catabolic process [IDA]
- positive regulation of cell migration [ISO]
- positive regulation of cell migration by vascular endothelial growth factor signaling pathway [ISO]
- positive regulation of protein targeting to membrane [ISO]
- positive regulation of vascular endothelial growth factor signaling pathway [ISO]
- protein targeting [ISO]
- protein targeting to membrane [ISO]
- regulation of tight junction assembly [ISO]
- transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- basal plasma membrane [ISO]
- brush border [ISO]
- cytoplasm [ISO]
- extracellular vesicular exosome [ISO]
- filamentous actin [ISO]
- lateral plasma membrane [ISO]
- membrane [ISO]
- membrane raft [IDA, ISO]
- microvillus [ISO]
- mitochondrion [ISO]
- myosin I complex [ISO]
- nucleoplasm [ISO]
- nucleus [IDA]
- plasma membrane [ISO]
- stereocilium [ISO]
- stress fiber [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1.
The heart undergoes pathological remodelling, featured by the hypertrophic growth of cardiomyocytes and increased cardiac fibrosis, under biomechanical stress such as haemodynamic overload. Ring Finger Protein 207 (RNF207) is an E3 ubiquitin ligase that is predominantly expressed in the heart, but its function remains elusive. In this study, we aimed to explore the role of RNF207 in the development of ... [more]
Cardiovasc Res Mar. 17, 2023; 119(1);183-194 [Pubmed: 35352799]
Throughput
- High Throughput
Curated By
- BioGRID