BAIT
RNF207
C1orf188
ring finger protein 207
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
CDH2
N-cadherin
cadherin 2
GO Process (19)
GO Function (9)
GO Component (15)
Gene Ontology Biological Process
- blood vessel morphogenesis [ISO]
- calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [IMP, ISO]
- cell adhesion [ISO]
- cell migration [ISO]
- cell-cell adhesion mediated by cadherin [ISO, ISS]
- glial cell differentiation [ISO, ISS]
- heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [ISO]
- homophilic cell adhesion via plasma membrane adhesion molecules [ISO]
- negative regulation of canonical Wnt signaling pathway [ISO]
- neuronal stem cell maintenance [ISO, ISS]
- positive regulation of MAPK cascade [ISO]
- protein heterooligomerization [IPI]
- regulation of Rho protein signal transduction [IMP]
- regulation of axonogenesis [IMP]
- regulation of myelination [IMP]
- regulation of protein localization [IMP]
- single organismal cell-cell adhesion [IDA]
- striated muscle cell differentiation [ISO]
- synapse assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- T-tubule [IDA]
- adherens junction [ISO]
- apical plasma membrane [ISO]
- catenin complex [ISO]
- cell-cell adherens junction [IDA, ISO]
- cell-cell junction [ISO]
- extracellular vesicular exosome [ISO]
- fascia adherens [IDA, ISO]
- focal adhesion [ISO]
- intercalated disc [IDA, ISO]
- lamellipodium [ISO]
- membrane [IDA]
- plasma membrane [IDA]
- protein complex [IDA]
- synapse [IDA, ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1.
The heart undergoes pathological remodelling, featured by the hypertrophic growth of cardiomyocytes and increased cardiac fibrosis, under biomechanical stress such as haemodynamic overload. Ring Finger Protein 207 (RNF207) is an E3 ubiquitin ligase that is predominantly expressed in the heart, but its function remains elusive. In this study, we aimed to explore the role of RNF207 in the development of ... [more]
Cardiovasc Res Mar. 17, 2023; 119(1);183-194 [Pubmed: 35352799]
Throughput
- High Throughput
Curated By
- BioGRID