BAIT
RNF207
C1orf188
ring finger protein 207
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
NCAM1
Cd56, N-CAM, N-CAM-1, NCAM-1, NCAM-C, NCAMC, Ncam
neural cell adhesion molecule 1
GO Process (23)
GO Function (6)
GO Component (11)
Gene Ontology Biological Process
- aging [IDA]
- calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [TAS]
- cell adhesion [TAS]
- cell surface receptor signaling pathway [ISO]
- cellular response to inorganic substance [IEP]
- cellular response to molecule of bacterial origin [IEP]
- homotypic cell-cell adhesion [ISO]
- learning or memory [IDA, IMP]
- multicellular organismal response to stress [IDA]
- negative regulation of cell death [IMP]
- neuron development [IDA]
- neuron projection development [ISO]
- organ regeneration [IEP]
- peripheral nervous system axon regeneration [IEP]
- positive regulation of calcium-mediated signaling [ISO]
- positive regulation of cardiac muscle cell proliferation [IMP]
- regulation of exocyst assembly [ISO]
- regulation of sensory perception of pain [IMP]
- response to cocaine [IDA]
- response to fluoxetine [IDA]
- response to inorganic substance [IEP]
- response to lead ion [IDA]
- thalamus development [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1.
The heart undergoes pathological remodelling, featured by the hypertrophic growth of cardiomyocytes and increased cardiac fibrosis, under biomechanical stress such as haemodynamic overload. Ring Finger Protein 207 (RNF207) is an E3 ubiquitin ligase that is predominantly expressed in the heart, but its function remains elusive. In this study, we aimed to explore the role of RNF207 in the development of ... [more]
Cardiovasc Res Mar. 17, 2023; 119(1);183-194 [Pubmed: 35352799]
Throughput
- High Throughput
Curated By
- BioGRID