BAIT

RNF207

C1orf188
ring finger protein 207
UPS Project
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

EEF1D

eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
GO Process (2)
GO Function (1)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Rattus norvegicus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1.

Yuan L, Bu S, Du M, Wang Y, Ju C, Huang D, Xu W, Tan X, Liang M, Deng S, Yang L, Huang K

The heart undergoes pathological remodelling, featured by the hypertrophic growth of cardiomyocytes and increased cardiac fibrosis, under biomechanical stress such as haemodynamic overload. Ring Finger Protein 207 (RNF207) is an E3 ubiquitin ligase that is predominantly expressed in the heart, but its function remains elusive. In this study, we aimed to explore the role of RNF207 in the development of ... [more]

Cardiovasc Res Mar. 17, 2023; 119(1);183-194 [Pubmed: 35352799]

Throughput

  • High Throughput

Curated By

  • BioGRID