BAIT
RNF207
C1orf188
ring finger protein 207
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
HSP90AB1
HSP90-BETA, HSP90B, HSPC2, Hspcb
heat shock protein 90 alpha (cytosolic), class B member 1
GO Process (14)
GO Function (13)
GO Component (12)
Gene Ontology Biological Process
- cellular response to interleukin-4 [ISO]
- cellular response to organic cyclic compound [IEP]
- negative regulation of neuron apoptotic process [IMP]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [ISO]
- placenta development [ISO]
- positive regulation of cell size [IMP]
- positive regulation of protein binding [IMP]
- positive regulation of protein import into nucleus, translocation [IMP]
- positive regulation of protein serine/threonine kinase activity [IMP]
- protein folding [TAS]
- regulation of interferon-gamma-mediated signaling pathway [ISO]
- regulation of type I interferon-mediated signaling pathway [ISO]
- response to salt stress [IEP]
- response to unfolded protein [TAS]
Gene Ontology Molecular Function- ATP binding [IDA, TAS]
- CTP binding [IDA]
- GTP binding [IDA]
- MHC class II protein complex binding [ISO]
- UTP binding [IDA]
- dATP binding [IDA]
- double-stranded RNA binding [ISO]
- ion channel binding [IPI]
- kinase binding [ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- sulfonylurea receptor binding [IPI]
- ATP binding [IDA, TAS]
- CTP binding [IDA]
- GTP binding [IDA]
- MHC class II protein complex binding [ISO]
- UTP binding [IDA]
- dATP binding [IDA]
- double-stranded RNA binding [ISO]
- ion channel binding [IPI]
- kinase binding [ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- sulfonylurea receptor binding [IPI]
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1.
The heart undergoes pathological remodelling, featured by the hypertrophic growth of cardiomyocytes and increased cardiac fibrosis, under biomechanical stress such as haemodynamic overload. Ring Finger Protein 207 (RNF207) is an E3 ubiquitin ligase that is predominantly expressed in the heart, but its function remains elusive. In this study, we aimed to explore the role of RNF207 in the development of ... [more]
Cardiovasc Res Mar. 17, 2023; 119(1);183-194 [Pubmed: 35352799]
Throughput
- High Throughput
Curated By
- BioGRID