BAIT
RNF207
C1orf188
ring finger protein 207
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
GNAI2
Galphai2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GO Process (14)
GO Function (5)
GO Component (12)
Gene Ontology Biological Process
- G-protein coupled acetylcholine receptor signaling pathway [ISO]
- G-protein coupled glutamate receptor signaling pathway [IDA]
- G-protein coupled receptor signaling pathway [IDA]
- activation of MAPKK activity [IMP]
- adenosine receptor signaling pathway [IDA]
- adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [IBA, ISO]
- cell division [ISO, ISS]
- cell proliferation [ISO]
- gamma-aminobutyric acid signaling pathway [IDA]
- intracellular signal transduction [IMP]
- negative regulation of synaptic transmission [IDA]
- positive regulation of cell proliferation [IMP]
- regulation of calcium ion transport [IDA]
- regulation of heart contraction [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1.
The heart undergoes pathological remodelling, featured by the hypertrophic growth of cardiomyocytes and increased cardiac fibrosis, under biomechanical stress such as haemodynamic overload. Ring Finger Protein 207 (RNF207) is an E3 ubiquitin ligase that is predominantly expressed in the heart, but its function remains elusive. In this study, we aimed to explore the role of RNF207 in the development of ... [more]
Cardiovasc Res Mar. 17, 2023; 119(1);183-194 [Pubmed: 35352799]
Throughput
- High Throughput
Curated By
- BioGRID