BAIT
RNF207
C1orf188
ring finger protein 207
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
VCL
vinculin
GO Process (10)
GO Function (4)
GO Component (16)
Gene Ontology Biological Process
- adherens junction assembly [ISO]
- apical junction assembly [ISO]
- axon extension [ISO]
- cell adhesion [ISO]
- epithelial cell-cell adhesion [ISO]
- lamellipodium assembly [ISO]
- morphogenesis of an epithelium [ISO]
- platelet aggregation [ISO]
- protein localization to cell surface [ISO]
- regulation of cell migration [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Z disc [IDA]
- actin filament [IDA]
- adherens junction [ISO]
- cell-cell adherens junction [ISO]
- cell-cell junction [ISO]
- costamere [ISO]
- cytoplasm [ISO]
- extracellular vesicular exosome [ISO]
- fascia adherens [ISO]
- focal adhesion [IDA, ISO]
- intercalated disc [IDA]
- plasma membrane [ISO]
- protein complex [ISO]
- sarcolemma [IDA]
- stress fiber [IDA]
- vesicle [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1.
The heart undergoes pathological remodelling, featured by the hypertrophic growth of cardiomyocytes and increased cardiac fibrosis, under biomechanical stress such as haemodynamic overload. Ring Finger Protein 207 (RNF207) is an E3 ubiquitin ligase that is predominantly expressed in the heart, but its function remains elusive. In this study, we aimed to explore the role of RNF207 in the development of ... [more]
Cardiovasc Res Mar. 17, 2023; 119(1);183-194 [Pubmed: 35352799]
Throughput
- High Throughput
Curated By
- BioGRID