BAIT
RNF207
C1orf188
ring finger protein 207
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
RTN4
NI-250, Nogo, Nogo-A, Vp20, r, rat N, rat NogoA
reticulon 4
GO Process (23)
GO Function (3)
GO Component (14)
Gene Ontology Biological Process
- aging [IEP]
- angiogenesis [ISO]
- axonal fasciculation [IDA, ISO]
- cardiac epithelial to mesenchymal transition [ISO]
- cerebral cortex radial glia guided migration [ISO, ISS]
- endoplasmic reticulum tubular network organization [ISO]
- negative regulation of axon extension [IDA, ISO, ISS]
- negative regulation of axonogenesis [IDA, IMP]
- negative regulation of cell growth [ISO]
- negative regulation of neuron differentiation [IDA]
- negative regulation of neuron projection development [IDA]
- negative regulation of neuron projection regeneration [IMP]
- nervous system development [ISO]
- olfactory nerve development [IEP]
- oligodendrocyte differentiation [IEP]
- positive regulation of dopamine secretion [IMP]
- positive regulation of glial cell differentiation [IDA]
- regulation of axon regeneration [IDA]
- regulation of branching morphogenesis of a nerve [IDA, ISO]
- regulation of cell migration [ISO]
- regulation of nervous system development [ISO]
- regulation of sensory perception of pain [IDA]
- response to activity [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell projection [ISO]
- cytoplasm [IDA]
- endoplasmic reticulum [IDA, ISO]
- extracellular vesicular exosome [ISO]
- integral component of endoplasmic reticulum membrane [IDA, ISO]
- integral component of membrane [TAS]
- intracellular [IDA, ISO]
- myelin sheath [IDA]
- neuron projection [IDA]
- neuronal cell body [IDA, ISO]
- neuronal postsynaptic density [ISO]
- nuclear envelope [ISO, ISS]
- plasma membrane [IDA]
- protein complex [IDA]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1.
The heart undergoes pathological remodelling, featured by the hypertrophic growth of cardiomyocytes and increased cardiac fibrosis, under biomechanical stress such as haemodynamic overload. Ring Finger Protein 207 (RNF207) is an E3 ubiquitin ligase that is predominantly expressed in the heart, but its function remains elusive. In this study, we aimed to explore the role of RNF207 in the development of ... [more]
Cardiovasc Res Mar. 17, 2023; 119(1);183-194 [Pubmed: 35352799]
Throughput
- High Throughput
Curated By
- BioGRID