BAIT
RNF207
C1orf188
ring finger protein 207
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
PRDX1
Hbp23
peroxiredoxin 1
GO Process (10)
GO Function (7)
GO Component (11)
Gene Ontology Biological Process
- cell proliferation [ISO]
- erythrocyte homeostasis [ISO]
- hydrogen peroxide catabolic process [ISO]
- natural killer cell mediated cytotoxicity [ISO]
- regulation of NF-kappaB import into nucleus [ISO]
- regulation of stress-activated MAPK cascade [ISO]
- removal of superoxide radicals [ISO]
- response to oxidative stress [IDA, ISO]
- response to reactive oxygen species [ISO]
- retina homeostasis [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1.
The heart undergoes pathological remodelling, featured by the hypertrophic growth of cardiomyocytes and increased cardiac fibrosis, under biomechanical stress such as haemodynamic overload. Ring Finger Protein 207 (RNF207) is an E3 ubiquitin ligase that is predominantly expressed in the heart, but its function remains elusive. In this study, we aimed to explore the role of RNF207 in the development of ... [more]
Cardiovasc Res Mar. 17, 2023; 119(1);183-194 [Pubmed: 35352799]
Throughput
- High Throughput
Curated By
- BioGRID