BAIT
RNF207
C1orf188
ring finger protein 207
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
DNAJB6
DnaJ (Hsp40) homolog, subfamily B, member 6
GO Process (12)
GO Function (5)
GO Component (7)
Gene Ontology Biological Process
- actin cytoskeleton organization [ISO]
- chorio-allantoic fusion [ISO]
- chorion development [ISO]
- extracellular matrix organization [ISO]
- intermediate filament organization [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of inclusion body assembly [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- positive regulation of ATPase activity [ISO]
- protein folding [ISO]
- protein localization to nucleus [ISO]
- syncytiotrophoblast cell differentiation involved in labyrinthine layer development [ISO]
Gene Ontology Molecular Function
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1.
The heart undergoes pathological remodelling, featured by the hypertrophic growth of cardiomyocytes and increased cardiac fibrosis, under biomechanical stress such as haemodynamic overload. Ring Finger Protein 207 (RNF207) is an E3 ubiquitin ligase that is predominantly expressed in the heart, but its function remains elusive. In this study, we aimed to explore the role of RNF207 in the development of ... [more]
Cardiovasc Res Mar. 17, 2023; 119(1);183-194 [Pubmed: 35352799]
Throughput
- High Throughput
Curated By
- BioGRID