BAIT

RAP1GAP

RAP1GA1, RAP1GAP1, RAP1GAPII, RAPGAP, RP11-63N8.1
RAP1 GTPase activating protein
Homo sapiens
PREY

MEX3A

MEX-3A, RKHD4
mex-3 RNA binding family member A
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Homo sapiens

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

Mex3a promotes oncogenesis through the RAP1/MAPK signaling pathway in colorectal cancer and is inhibited by hsa-miR-6887-3p.

Li H, Liang J, Wang J, Han J, Li S, Huang K, Liu C

Although Mex3 RNA-binding family member A (Mex3a) has demonstrated an important role in multiple cancers, its role and regulatory mechanism in CRC is unclear. In this study, we aimed to investigate the role and clinical significance of Mex3a in CRC and to explore its underlying mechanism.Western blotting and quantitative real-time polymerase chain reaction (qRT-PCR) were performed to detect the expression ... [more]

Cancer Commun (Lond) Jun. 01, 2021; 41(6);472-491 [Pubmed: 33638620]

Throughput

  • Low Throughput

Curated By

  • BioGRID