BAIT
RAB1A
RAB1, YPT1
RAB1A, member RAS oncogene family
GO Process (19)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- ER to Golgi vesicle-mediated transport [IGI, IMP]
- GTP catabolic process [IDA]
- Golgi organization [IMP]
- Rab protein signal transduction [IBA]
- autophagic vacuole assembly [IMP]
- autophagy [IMP]
- cargo loading into COPII-coated vesicle [IMP]
- cell migration [IMP]
- cilium assembly [IMP]
- defense response to bacterium [IMP]
- endocytosis [IMP]
- growth hormone secretion [IMP]
- interleukin-8 secretion [IMP]
- intracellular protein transport [IBA]
- mitotic cell cycle [TAS]
- positive regulation of glycoprotein metabolic process [IGI]
- vesicle transport along microtubule [IMP]
- vesicle-mediated transport [TAS]
- virion assembly [IGI, IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SSX2IP
ADIP
synovial sarcoma, X breakpoint 2 interacting protein
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Deconvolution of Multiple Rab Binding Domains Using the Batch Yeast 2-Hybrid Method DEEPN.
A hallmark of functionally significant interactions between Rab proteins and their targets is whether that binding depends on the type of nucleotide bound to the Rab GTPase. A system that can directly compare those sets of interactions mediated by a Rab in its GTP-bound conformation versus its GDP bound conformation would provide a direct route to finding biologically relevant partners. ... [more]
Methods Mol Biol Aug. 29, 2021; 2293();117-141 [Pubmed: 34453714]
Throughput
- Low Throughput
Curated By
- BioGRID