IHH
Gene Ontology Biological Process
- bone resorption [IDA]
- camera-type eye development [IMP]
- camera-type eye photoreceptor cell fate commitment [IMP]
- cartilage development [IMP]
- cell differentiation [IDA]
- cell fate specification [IMP]
- cell maturation [IMP]
- chondrocyte proliferation [IMP]
- embryo development [IMP]
- embryonic camera-type eye morphogenesis [IMP]
- embryonic digestive tract morphogenesis [IMP]
- embryonic pattern specification [IMP]
- embryonic skeletal joint development [IMP]
- epithelial cell morphogenesis [IMP]
- epithelial cell-cell adhesion [IMP]
- head morphogenesis [IMP]
- heart looping [IMP]
- in utero embryonic development [IMP]
- morphogenesis of a branching structure [IMP]
- multicellular organism growth [IMP]
- negative regulation of T cell differentiation in thymus [IMP]
- negative regulation of alpha-beta T cell differentiation [IMP]
- negative regulation of apoptotic process [ISO]
- negative regulation of cell differentiation [IMP]
- negative regulation of eye pigmentation [IMP]
- negative regulation of immature T cell proliferation in thymus [IMP]
- negative regulation of signal transduction [ISO]
- neuron development [IMP]
- ossification [IMP]
- osteoblast differentiation [IMP]
- pancreas development [IGI, IMP]
- pattern specification process [IMP]
- patterning of blood vessels [IMP]
- positive regulation of T cell differentiation in thymus [IMP]
- positive regulation of alpha-beta T cell differentiation [IMP]
- positive regulation of cell proliferation [IGI, IMP]
- positive regulation of chondrocyte differentiation [ISO]
- positive regulation of collagen biosynthetic process [IDA]
- positive regulation of epithelial cell proliferation [ISO]
- positive regulation of mesenchymal cell proliferation [IMP]
- positive regulation of smoothened signaling pathway [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IGI, ISO]
- proteoglycan metabolic process [IGI]
- regulation of cell differentiation [ISO]
- regulation of growth [IGI]
- retinal pigment epithelium development [IMP]
- skeletal system development [IMP, ISO]
- smooth muscle tissue development [IMP]
- smoothened signaling pathway [IGI, ISO]
- somite development [IMP]
- vasculature development [IMP]
- vitelline membrane formation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
GPC3
Gene Ontology Biological Process
- anterior/posterior axis specification [IGI]
- body morphogenesis [IMP]
- bone mineralization [IMP]
- branching involved in ureteric bud morphogenesis [IGI]
- cell proliferation involved in kidney development [IMP]
- cell proliferation involved in metanephros development [IMP]
- coronary vasculature development [IMP]
- embryonic hindlimb morphogenesis [IGI]
- kidney development [IMP]
- lung development [IMP]
- mesenchymal cell proliferation involved in ureteric bud development [IMP]
- mesonephric duct morphogenesis [IMP]
- negative regulation of canonical Wnt signaling pathway [IMP, ISO]
- negative regulation of cell proliferation [IGI]
- negative regulation of epithelial cell proliferation [IMP]
- negative regulation of growth [IMP]
- negative regulation of peptidase activity [ISO]
- negative regulation of smoothened signaling pathway [IGI, IMP]
- organ morphogenesis [IMP]
- osteoclast differentiation [IMP]
- positive regulation of BMP signaling pathway [IMP]
- positive regulation of Wnt signaling pathway, planar cell polarity pathway [IMP, ISO]
- positive regulation of endocytosis [IDA]
- positive regulation of glucose import [IDA]
- positive regulation of protein catabolic process [IDA]
- positive regulation of smoothened signaling pathway [IMP]
- regulation of growth [IGI, IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex.
Previous studies from our laboratory have found glypican 3 (GPC3) as a negative regulator of growth. CD81 was found to be a binding partner for GPC3, and its expression and co-localization with GPC3 increased at the end of hepatocyte proliferation. However, the mechanisms through which these two molecules might regulate liver regeneration are not known. We tested the hypothesis that ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID