BAIT

METTL5

HSPC133, DC3
methyltransferase like 5
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

SKP2

FBL1, FBXL1, FLB1, p45
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
UPS Project
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

METTL5 stabilizes c-Myc by facilitating USP5 translation to reprogram glucose metabolism and promote hepatocellular carcinoma progression.

Xia P, Zhang H, Lu H, Xu K, Jiang X, Jiang Y, Gongye X, Chen Z, Liu J, Chen X, Ma W, Zhang Z, Yuan Y

Hepatocellular carcinoma (HCC) is one of the most prevalent cancers in the world, with a high likelihood of metastasis and a dismal prognosis. The reprogramming of glucose metabolism is critical in the development of HCC. The Warburg effect has recently been confirmed to occur in a variety of cancers, including HCC. However, little is known about the molecular biological mechanisms ... [more]

Cancer Commun (Lond) Mar. 01, 2023; 43(3);338-364 [Pubmed: 36602428]

Throughput

  • Low Throughput

Curated By

  • BioGRID