BAIT

AK6

AD-004, CGI-137, CINAP, CIP, hCINAP
adenylate kinase 6
GO Process (1)
GO Function (2)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

LDHA

GSD11, HEL-S-133P, LDH1, LDHM, PIG19
lactate dehydrogenase A
Human Papilloma Virus (HPV) Project
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

hCINAP regulates the differentiation of embryonic stem cells by regulating NEDD4 liquid-liquid phase-separation-mediated YAP1 activation.

Zhuge R, Wang C, Wang J, Yu S, Liao L, Zheng X

YAP1 functions in lineage differentiation of pluripotent embryonic stem cells (ESCs); however, the detailed mechanisms underlying the regulation of YAP1 activity during ESC differentiation remain elusive. Here, we report that hCINAP serves as a negative regulator of YAP1 during ESC fate decisions. The expression of mCINAP, the murine homolog of hCINAP, is downregulated during the differentiation process of murine ESC ... [more]

Cell Rep Jan. 31, 2023; 42(1);111935 [Pubmed: 36640330]

Throughput

  • High Throughput

Curated By

  • BioGRID