BAIT
GRM2
GLUR2, GPRC1B, MGLUR2, mGlu2
glutamate receptor, metabotropic 2
GO Process (4)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
YBX3
CSDA, CSDA1, DBPA, ZONAB
Y box binding protein 3
GO Process (7)
GO Function (6)
GO Component (4)
Gene Ontology Biological Process
- 3'-UTR-mediated mRNA stabilization [IC]
- cellular hyperosmotic response [IMP]
- cellular response to tumor necrosis factor [IMP]
- negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [IMP]
- negative regulation of necroptotic process [IMP]
- positive regulation of cytoplasmic translation [ISS]
- response to cold [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.
Identification of bona fide functional receptors and elucidation of the mechanism of receptor-mediated virus entry are important to reveal targets for developing therapeutics against rabies virus (RABV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Our previous studies suggest that metabotropic glutamate receptor subtype 2 (mGluR2) functions as an entry receptor for RABV in vitro, and is an important internalization ... [more]
J Virol Feb. 28, 2023; 97(2);e0161122 [Pubmed: 36779763]
Throughput
- High Throughput
Additional Notes
- Affinity capture-MS was carried out to identify high confidence protein interactors with the number of unique peptides being greater than or equal to 2 times over control in at least 2 replicates
Curated By
- BioGRID