BAIT
GRM2
GLUR2, GPRC1B, MGLUR2, mGlu2
glutamate receptor, metabotropic 2
GO Process (4)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
EXOSC3
PCH1B, RRP40, Rrp40p, bA3J10.7, hRrp-40, p10, CGI-102
exosome component 3
GO Process (16)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
- CUT catabolic process [IMP]
- DNA deamination [IDA]
- RNA metabolic process [TAS]
- U4 snRNA 3'-end processing [IBA]
- exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [IMP, TAS]
- exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [IBA]
- gene expression [TAS]
- isotype switching [ISS]
- mRNA metabolic process [TAS]
- nuclear polyadenylation-dependent rRNA catabolic process [IBA]
- nuclear polyadenylation-dependent tRNA catabolic process [IBA]
- nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [IBA]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
- nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [IBA]
- polyadenylation-dependent snoRNA 3'-end processing [IBA]
- rRNA processing [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.
Identification of bona fide functional receptors and elucidation of the mechanism of receptor-mediated virus entry are important to reveal targets for developing therapeutics against rabies virus (RABV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Our previous studies suggest that metabotropic glutamate receptor subtype 2 (mGluR2) functions as an entry receptor for RABV in vitro, and is an important internalization ... [more]
J Virol Feb. 28, 2023; 97(2);e0161122 [Pubmed: 36779763]
Throughput
- High Throughput
Additional Notes
- Affinity capture-MS was carried out to identify high confidence protein interactors with the number of unique peptides being greater than or equal to 2 times over control in at least 2 replicates
Curated By
- BioGRID