BAIT

GRM2

GLUR2, GPRC1B, MGLUR2, mGlu2
glutamate receptor, metabotropic 2
Homo sapiens
PREY

SLC25A6

2, 3, AAC3, ANT, ANT 2, ANT 3, ANT3, ANT3Y, RP11-261P4.6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.

Wang X, Wen Z, Cao H, Luo J, Shuai L, Wang C, Ge J, Wang X, Bu Z, Wang J

Identification of bona fide functional receptors and elucidation of the mechanism of receptor-mediated virus entry are important to reveal targets for developing therapeutics against rabies virus (RABV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Our previous studies suggest that metabotropic glutamate receptor subtype 2 (mGluR2) functions as an entry receptor for RABV in vitro, and is an important internalization ... [more]

J Virol Feb. 28, 2023; 97(2);e0161122 [Pubmed: 36779763]

Throughput

  • High Throughput

Additional Notes

  • Affinity capture-MS was carried out to identify high confidence protein interactors with the number of unique peptides being greater than or equal to 2 times over control in at least 2 replicates

Curated By

  • BioGRID