MLST8
Gene Ontology Biological Process
Gene Ontology Cellular Component
RICTOR
Gene Ontology Biological Process
- actin cytoskeleton reorganization [ISO]
- embryo development [IMP]
- peptidyl-serine phosphorylation [ISO]
- positive regulation of TOR signaling [ISO]
- positive regulation of actin filament polymerization [IMP]
- positive regulation of endothelial cell proliferation [ISO]
- positive regulation of peptidyl-tyrosine phosphorylation [IMP]
- positive regulation of protein kinase B signaling [ISO]
- regulation of Rac GTPase activity [IMP]
- regulation of actin cytoskeleton organization [ISO]
- regulation of phosphorylation [ISO]
- regulation of protein kinase B signaling [IDA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- TORC2 complex [IDA, ISO]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Maternal hyperglycemia inhibits pulmonary vasculogenesis during mouse fetal lung development by promoting G?L Ubiquitination-dependent mammalian target of Rapamycin assembly.
Gestational diabetes mellitus (GDM) is associated with retarded lung development and poor lung health in offspring. Mammalian target of rapamycin (mTOR) is a key regulator of vasculogenesis and angiogenesis. The aim of this study was to investigate the role mTOR plays in pulmonary vasculogenesis during fetal lung development under maternal hyperglycemia.First, GDM was induced via streptozotocin injection in pregnant C57BL/6 ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RICTOR MLST8 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID