BAIT
OTUD1
DUBA7, OTDC1
OTU deubiquitinase 1
GO Process (1)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
HSP90AB1
D6S182, HSP84, HSP90B, HSPC2, HSPCB, RP1-302G2.1
heat shock protein 90kDa alpha (cytosolic), class B member 1
GO Process (9)
GO Function (7)
GO Component (6)
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- axon guidance [TAS]
- innate immune response [TAS]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [TAS]
- positive regulation of nitric oxide biosynthetic process [ISS]
- regulation of interferon-gamma-mediated signaling pathway [IMP]
- regulation of type I interferon-mediated signaling pathway [IMP]
- response to unfolded protein [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinoma.
The deubiquitinase ovarian tumor domain-containing 1 (OTUD1) has been considered as a tumor suppressor in many tumors, but there is minimal research on the role of OTUD1 in lung adenocarcinoma (LUAD) pathogenesis.Bioinformatics analyses and western blot were applied for investigating OTUD1 expression in lung cancer and the drug that upregulated OTUD1. Kaplan-Meier analysis with log-rank test was used for survival ... [more]
Cell Oncol (Dordr) Aug. 01, 2023; 46(4);1001-1014 [Pubmed: 36929488]
Throughput
- Low Throughput
Curated By
- BioGRID