SUA7
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RAP1
Gene Ontology Biological Process
- chromatin organization involved in regulation of transcription [IDA]
- chromatin silencing at silent mating-type cassette [IGI]
- chromatin silencing at telomere [IGI]
- establishment of chromatin silencing at telomere [IPI]
- establishment of protein localization to chromatin [IPI]
- establishment of protein localization to telomere [IPI]
- negative regulation of chromatin silencing [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- protection from non-homologous end joining at telomere [IMP]
- regulation of glycolytic by positive regulation of transcription from RNA polymerase II promoter [IGI]
- telomere maintenance [IMP]
- telomere maintenance via telomere lengthening [IDA, IMP]
Gene Ontology Molecular Function- DNA binding, bending [IDA]
- G-quadruplex DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription factor binding transcription factor activity [IDA]
- TBP-class protein binding RNA polymerase II transcription factor activity [IDA]
- TFIID-class transcription factor binding [IDA]
- core promoter proximal region sequence-specific DNA binding [IDA]
- nucleosomal DNA binding [IDA]
- sequence-specific DNA binding [IDA]
- telomeric DNA binding [IDA]
- DNA binding, bending [IDA]
- G-quadruplex DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription factor binding transcription factor activity [IDA]
- TBP-class protein binding RNA polymerase II transcription factor activity [IDA]
- TFIID-class transcription factor binding [IDA]
- core promoter proximal region sequence-specific DNA binding [IDA]
- nucleosomal DNA binding [IDA]
- sequence-specific DNA binding [IDA]
- telomeric DNA binding [IDA]
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle.
Although TFIIB is widely regarded as an initiation factor, recent reports have implicated it in multiple aspects of eukaryotic transcription. To investigate the broader role of TFIIB in transcription, we performed quantitative proteomic analysis of yeast TFIIB. We purified two different populations of TFIIB; one from soluble cell lysate, which is not engaged in transcription, and the other from the ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RAP1 SUA7 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.2042 | BioGRID | 1876086 | |
| RAP1 SUA7 | Positive Genetic Positive Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a less severe fitness defect than expected under a given condition. This term is reserved for high or low throughput studies with scores. | High | 0.1738 | BioGRID | 1876085 |
Curated By
- BioGRID