BAIT
MCAM
CD146, MUC18
melanoma cell adhesion molecule
GO Process (4)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
STRA6
MCOPCB8, MCOPS9, PP14296
stimulated by retinoic acid 6
GO Process (36)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
- adrenal gland development [IMP]
- alveolar primary septum development [IMP]
- artery morphogenesis [IMP]
- blood vessel development [IMP]
- cognition [IMP]
- developmental growth [IMP]
- diaphragm development [IMP]
- digestive tract morphogenesis [IMP]
- ductus arteriosus closure [IMP]
- ear development [IMP]
- embryonic camera-type eye formation [IMP]
- embryonic digestive tract development [IMP]
- eyelid development in camera-type eye [IMP]
- face morphogenesis [IMP]
- feeding behavior [IMP]
- female genitalia development [IMP]
- head development [IMP]
- head morphogenesis [IMP]
- heart development [IMP]
- kidney development [IMP]
- learning [IMP]
- lung alveolus development [IMP]
- lung development [IMP]
- lung vasculature development [IMP]
- neuromuscular process [IMP]
- nose morphogenesis [IMP]
- paramesonephric duct development [IMP]
- phototransduction, visible light [TAS]
- positive regulation of behavior [IMP]
- pulmonary artery morphogenesis [IMP]
- pulmonary valve morphogenesis [IMP]
- retinoid metabolic process [TAS]
- smooth muscle tissue development [IMP]
- uterus morphogenesis [IMP]
- ventricular septum development [IMP]
- vocal learning [IMP]
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.
The WRAMP structure is a protein network associated with tail-end actomyosin contractility, membrane retraction, and directional persistence during cell migration. A marker of WRAMP structures is melanoma cell adhesion molecule (MCAM) which dynamically polarizes to the cell rear. However, factors that mediate MCAM polarization are still unknown. In this study, BioID using MCAM as bait identifies the ERM family proteins, ... [more]
Mol Biol Cell Dec. 20, 2023; ();mbcE23060255 [Pubmed: 38117590]
Throughput
- High Throughput
Additional Notes
- BioID
- Samples with a SAINT score corresponding to an FDR less than 0.05 were considered significant
Curated By
- BioGRID