BAIT
MCAM
CD146, MUC18
melanoma cell adhesion molecule
GO Process (4)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
MINK1
B55, MAP4K6, MINK, YSK2, ZC3, hMINK, hMINKbeta
misshapen-like kinase 1
GO Process (14)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- JNK cascade [TAS]
- actin cytoskeleton reorganization [IMP]
- dendrite morphogenesis [ISS]
- intracellular signal transduction [ISS]
- multicellular organismal development [ISS]
- positive regulation of JNK cascade [IMP]
- protein autophosphorylation [IDA]
- protein phosphorylation [ISS]
- regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [ISS]
- regulation of cell migration [IMP]
- regulation of cell-cell adhesion [IMP]
- regulation of cell-matrix adhesion [IMP]
- response to stress [ISS]
- synaptic transmission [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.
The WRAMP structure is a protein network associated with tail-end actomyosin contractility, membrane retraction, and directional persistence during cell migration. A marker of WRAMP structures is melanoma cell adhesion molecule (MCAM) which dynamically polarizes to the cell rear. However, factors that mediate MCAM polarization are still unknown. In this study, BioID using MCAM as bait identifies the ERM family proteins, ... [more]
Mol Biol Cell Dec. 20, 2023; ();mbcE23060255 [Pubmed: 38117590]
Throughput
- High Throughput
Additional Notes
- BioID
- Samples with a SAINT score corresponding to an FDR less than 0.05 were considered significant
Curated By
- BioGRID