BAIT
UBA52
Rps27a, Ubb
ubiquitin A-52 residue ribosomal protein fusion product 1
GO Process (0)
GO Function (0)
GO Component (4)
Gene Ontology Cellular Component
Rattus norvegicus
PREY
PKLR
PK1, PKL, Pklg
pyruvate kinase, liver and RBC
GO Process (15)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- ATP biosynthetic process [IDA]
- carbohydrate metabolic process [IDA]
- cellular response to insulin stimulus [IDA]
- glycolytic process [IDA]
- pyruvate biosynthetic process [IDA]
- response to ATP [IDA]
- response to cAMP [IDA]
- response to glucose [IEP]
- response to heat [IDA]
- response to hypoxia [IEP]
- response to lithium ion [IDA]
- response to metal ion [IEP]
- response to nutrient [IEP]
- response to organic cyclic compound [IEP]
- response to other organism [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
UBA52 Attunes VDAC1-Mediated Mitochondrial Dysfunction and Dopaminergic Neuronal Death.
Mitochondrial homeostasis regulates energy metabolism, calcium buffering, cell function, and apoptosis. The present study has been conducted to investigate the implications of the ubiquitin-encoding gene UBA52 in mitochondrial physiology. Transient expression of Myc-UBA52 in neurons significantly inhibited the rotenone-induced increase in reactive oxygen species generation, nitrite level, and depleted glutathione level. Mass spectrometric and coimmunoprecipitation data suggested the profound interaction ... [more]
ACS Chem Neurosci Mar. 01, 2023; 14(5);839-850 [Pubmed: 36755387]
Throughput
- Low Throughput
Curated By
- BioGRID