ACE2
Gene Ontology Biological Process
- angiotensin catabolic process in blood [IC]
- angiotensin maturation [TAS]
- angiotensin-mediated drinking behavior [IMP]
- cellular protein metabolic process [TAS]
- positive regulation of reactive oxygen species metabolic process [IC]
- receptor biosynthetic process [IMP]
- receptor-mediated virion attachment to host cell [IDA]
- regulation of cell proliferation [TAS]
- regulation of cytokine production [IC]
- regulation of inflammatory response [IC]
- regulation of systemic arterial blood pressure by renin-angiotensin [IC, IMP]
- regulation of vasoconstriction [IC]
- regulation of vasodilation [IC]
- response to virus [IDA, IMP]
- viral entry into host cell [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RPL7
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- rRNA processing [IMP]
- ribosomal large subunit biogenesis [IMP]
- translation [NAS, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly.
Considerable progress has been made in understanding the molecular host-virus battlefield during SARS-CoV-2 infection. Nevertheless, the assembly and egress of newly formed virions are less understood. To identify host proteins involved in viral morphogenesis, we characterize the proteome of SARS-CoV-2 virions produced from A549-ACE2 and Calu-3 cells, isolated via ultracentrifugation on sucrose cushion or by ACE-2 affinity capture. Bioinformatic analysis ... [more]
Throughput
- High Throughput
Additional Notes
- SARS-CoV-2 infected A549-ACE2 cells
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ACE2 RPL7 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - | |
| ACE2 RPL7 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 3750685 |
Curated By
- BioGRID