BAIT
SLC9A9
AUTS16, NHE9, Nbla00118
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
VIM
CTRCT30, HEL113, RP11-124N14.1
vimentin
GO Process (4)
GO Function (7)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Effect of disease-associated SLC9A9 mutations on protein-protein interaction networks: implications for molecular mechanisms for ADHD and autism.
Na+/H+ Exchanger 9 (NHE9) is an endosomal membrane protein encoded by the Solute Carrier 9A, member 9 gene (SLC9A9). SLC9A9 has been implicated in attention deficit hyperactivity disorder (ADHD), autism spectrum disorders (ASDs), epilepsy, multiple sclerosis and cancers. To better understand the function of NHE9 and the effects of disease-associated variants on protein-protein interactions, we conducted a quantitative analysis of ... [more]
Atten Defic Hyperact Disord Mar. 01, 2019; 11(1);91-105 [Pubmed: 30927234]
Throughput
- High Throughput
Additional Notes
- A409P (AP) mutant NHE9
- Decreased interaction with NHE9 due to the A409P mutation.
- Wild type NHE9
Curated By
- BioGRID