BAIT
EFNA1
B61, ECKLG, EFL1, EPLG1, LERK-1, LERK1, TNFAIP4
ephrin-A1
GO Process (15)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- angiogenesis [IBA]
- aortic valve morphogenesis [ISS]
- axon guidance [IBA]
- cell migration [IDA]
- cell-cell signaling [TAS]
- endocardial cushion to mesenchymal transition involved in heart valve formation [ISS]
- ephrin receptor signaling pathway [IDA]
- mitral valve morphogenesis [ISS]
- negative regulation of dendritic spine morphogenesis [ISS]
- negative regulation of epithelial to mesenchymal transition [ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of peptidyl-tyrosine phosphorylation [IDA]
- regulation of cell adhesion mediated by integrin [IDA]
- regulation of peptidyl-tyrosine phosphorylation [ISS]
- substrate adhesion-dependent cell spreading [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
EEF1A1
CCS-3, CCS3, EE1A1, EEF-1, EEF1A, EF-Tu, EF1A, GRAF-1EF, HNGC:16303, LENG7, PTI1, eEF1A-1, RP11-505P4.2
eukaryotic translation elongation factor 1 alpha 1
GO Process (5)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Ephrin-As, Eph receptors and integrin ?3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells.
Glioblastoma is the most common brain cancer. Ephrins and their Eph receptors play important roles in the development of central nervous system and the regulation of cancer cell migration and invasion. In a search for the Eph receptor complexes, we used tandem affinity purification based interaction screening with tagged ephrins A1, A3 and A4 combined with protein identification by mass-spectrometry ... [more]
Cell Biol Int Oct. 01, 2013; 37(10);1080-8 [Pubmed: 23686814]
Throughput
- Low Throughput
Curated By
- BioGRID