BAIT
EFNA3
EFL2, EPLG3, Ehk1-L, LERK3
ephrin-A3
GO Process (3)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
WNT7A
wingless-type MMTV integration site family, member 7A
GO Process (22)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- Wnt signaling pathway involved in wound healing, spreading of epidermal cells [IDA]
- canonical Wnt signaling pathway [IDA]
- cartilage condensation [IDA]
- cell fate commitment [IBA]
- cell proliferation in forebrain [IDA]
- cellular response to transforming growth factor beta stimulus [IEP]
- chondrocyte differentiation [IDA]
- embryonic axis specification [IMP]
- embryonic digit morphogenesis [IMP]
- embryonic forelimb morphogenesis [IMP]
- embryonic hindlimb morphogenesis [IMP]
- lens fiber cell development [ISS]
- negative regulation of neurogenesis [IDA]
- neuron differentiation [IBA]
- palate development [IMP]
- positive regulation of JNK cascade [IBA]
- positive regulation of epithelial cell proliferation involved in wound healing [IDA]
- positive regulation of synapse assembly [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- sex differentiation [TAS]
- stem cell development [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Ephrin-As, Eph receptors and integrin ?3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells.
Glioblastoma is the most common brain cancer. Ephrins and their Eph receptors play important roles in the development of central nervous system and the regulation of cancer cell migration and invasion. In a search for the Eph receptor complexes, we used tandem affinity purification based interaction screening with tagged ephrins A1, A3 and A4 combined with protein identification by mass-spectrometry ... [more]
Cell Biol Int Oct. 01, 2013; 37(10);1080-8 [Pubmed: 23686814]
Throughput
- Low Throughput
Curated By
- BioGRID