BAIT
CEMIP
CCSP1, KIAA1199, TMEM2L
cell migration inducing protein, hyaluronan binding
GO Process (7)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- hyaluronan catabolic process [IMP]
- positive regulation of cell migration [IDA]
- positive regulation of peptidyl-threonine phosphorylation [IDA]
- positive regulation of protein kinase C activity [IDA]
- positive regulation of protein targeting to membrane [IDA]
- positive regulation of release of sequestered calcium ion into cytosol [IDA]
- sensory perception of sound [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
GNB1
RP1-283E3.7
guanine nucleotide binding protein (G protein), beta polypeptide 1
GO Process (16)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
- G-protein coupled acetylcholine receptor signaling pathway [TAS]
- GTP catabolic process [IDA, TAS]
- Ras protein signal transduction [TAS]
- adenylate cyclase-activating dopamine receptor signaling pathway [ISS]
- blood coagulation [TAS]
- cellular response to catecholamine stimulus [ISS]
- cellular response to glucagon stimulus [TAS]
- cellular response to prostaglandin E stimulus [ISS]
- energy reserve metabolic process [TAS]
- phototransduction, visible light [TAS]
- platelet activation [TAS]
- regulation of rhodopsin mediated signaling pathway [TAS]
- rhodopsin mediated signaling pathway [TAS]
- signal transduction [TAS]
- small molecule metabolic process [TAS]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
CEMIP, acting as a scaffold protein for bridging GRAF1 and MIB1, promotes colorectal cancer metastasis via activating CDC42/MAPK pathway.
Metastasis is the leading cause of treatment failure and tumor-related death in colorectal cancer (CRC). Our previous studies report that CEMIP functionally promotes CRC metastasis and is closely related to poor outcomes. However, the molecular network of CEMIP promoting CRC metastasis is still not fully understood. In the current study, we identify CEMIP interacting with GRAF1, and the combination of ... [more]
Cell Death Dis Feb. 27, 2023; 14(2);167 [Pubmed: 36849460]
Throughput
- Low Throughput
Curated By
- BioGRID