BAIT

RNF138

2410015A17Rik, 2810480D20Rik, STRIN, Trif, Trif-d
ring finger protein 138
GO Process (0)
GO Function (1)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus
PREY

PLEC

AA591047, AU042537, EBS1, PCN, PLTN, Plec1
plectin
Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.

Liu W, Wang Z, Liu S, Zhang X, Cao X, Jiang M

As one of the core components of the switching or sucrose non-fermentable (SWI/SNF) complex, SMARCC1 (BAF155, SRG3) plays essential roles in activation of late inflammatory genes in response to microbial challenge. However, little is known about the mechanism of how SMARCC1 regulates the inflammatory innate response. Via functional screening, we identify the nuclear E3 ubiquitin ligase RNF138 as a negative ... [more]

Cell Rep Feb. 28, 2023; 42(2);112097 [Pubmed: 36800290]

Throughput

  • High Throughput

Curated By

  • BioGRID