An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Publication

circFNDC3B Accelerates Vasculature Formation and Metastasis in Oral Squamous Cell Carcinoma.

Li X, Wang C, Zhang H, Li Y, Hou D, Liu D, Xu R, Cheng J, Liu L, Fu Y, Ye J, Jiang H

Emerging evidence has demonstrated that circular RNAs (circRNA) are involved in cancer metastasis. Further elucidation of the role of circRNAs in oral squamous cell carcinoma (OSCC) could provide insights into mechanisms driving metastasis and potential therapeutic targets. Here, we identify a circRNA, circFNDC3B, that is significantly upregulated in OSCC and is positively associated with lymph node (LN) metastasis. In vitro ... [more]

Cancer Res May. 02, 2023; 83(9);1459-1475 [Pubmed: 36811957]

Throughput

Low Throughput

Additional Notes

Hit is circFNDC3B

Related interactions

Interaction	Experimental Evidence Code	Dataset	Throughput	Score	Curated By	Notes
FNDC3B FUS	Protein-RNA Protein-RNA An interaction is detected between and protein and an RNA in vitro.	Li X (2023)	Low/High	-	BioGRID	3652268

Curated By

BioGRID

Interaction Summary

FUS

Gene Ontology Biological Process

Gene Ontology Molecular Function

RNA binding [TAS]identical protein binding [IPI]poly(A) RNA binding [IDA]protein binding [IPI]

Gene Ontology Cellular Component

FNDC3B