BAIT
MUC1
ADMCKD, ADMCKD1, CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM, RP11-263K19.2
mucin 1, cell surface associated
GO Process (10)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [IDA]
- DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [IDA]
- O-glycan processing [TAS]
- cellular protein metabolic process [TAS]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IDA]
- negative regulation of transcription by competitive promoter binding [IDA]
- positive regulation of histone H4 acetylation [IDA]
- positive regulation of transcription from RNA polymerase II promoter in response to stress [IDA]
- post-translational protein modification [TAS]
- regulation of transcription from RNA polymerase II promoter in response to stress [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SEC22B
ERS-24, SEC22L1
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
GO Process (3)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Assessment of community efforts to advance network-based prediction of protein-protein interactions.
Comprehensive understanding of the human protein-protein interaction (PPI) network, aka the human interactome, can provide important insights into the molecular mechanisms of complex biological processes and diseases. Despite the remarkable experimental efforts undertaken to date to determine the structure of the human interactome, many PPIs remain unmapped. Computational approaches, especially network-based methods, can facilitate the identification of previously uncharacterized PPIs. ... [more]
Nat Commun Mar. 22, 2023; 14(1);1582 [Pubmed: 36949045]
Throughput
- High Throughput
Curated By
- BioGRID