FOXP1
Gene Ontology Biological Process
- T follicular helper cell differentiation [ISS]
- chemokine (C-C motif) ligand 2 secretion [IDA]
- endothelial cell activation [IMP]
- interleukin-21 secretion [ISS]
- macrophage activation [IDA]
- monocyte activation [IDA]
- negative regulation of B cell apoptotic process [IDA]
- negative regulation of androgen receptor signaling pathway [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- osteoclast development [IDA]
- osteoclast differentiation [IDA]
- positive regulation of endothelial cell migration [IMP]
- positive regulation of smooth muscle cell proliferation [IMP]
- regulation of defense response to bacterium [IDA]
- regulation of endothelial tube morphogenesis [IMP]
- regulation of inflammatory response [IDA]
- regulation of interleukin-1 beta secretion [IDA]
- regulation of interleukin-12 secretion [IDA]
- regulation of macrophage colony-stimulating factor production [IDA]
- regulation of monocyte differentiation [IDA]
- regulation of transcription from RNA polymerase II promoter [IBA]
- regulation of tumor necrosis factor production [IDA]
- response to lipopolysaccharide [IDA]
- transcription from RNA polymerase II promoter [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleoplasm [IDA]
- nucleus [IDA]
PTBP1
Gene Ontology Biological Process
- RNA splicing [TAS]
- gene expression [TAS]
- mRNA processing [TAS]
- mRNA splicing, via spliceosome [TAS]
- negative regulation of RNA splicing [IDA]
- negative regulation of mRNA splicing, via spliceosome [IDA]
- negative regulation of muscle cell differentiation [IDA]
- regulation of alternative mRNA splicing, via spliceosome [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
Circular RNA FOXP1 promotes tumor progression and Warburg effect in gallbladder cancer by regulating PKLR expression.
Circular RNAs (circRNAs) have recently been identified as potential functional modulators of the cellular physiology processes. The study aims to uncover the potential clinical value and driving molecular mechanisms of circRNAs in gallbladder cancer (GBC).We performed RNA sequencing from four GBC and paired adjacent normal tissues to analyze the circRNA candidates. Quantitative real-time polymerase chain reaction (QRT-PCR) was used to ... [more]
Throughput
- High Throughput|Low Throughput
Additional Notes
- Bait is circFOXP1
- HTP hit identified by MS
- LTP hit identified by western
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| PTBP1 FOXP1 | Affinity Capture-RNA Affinity Capture-RNA An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis. | Low | - | BioGRID | 3674985 |
Curated By
- BioGRID