BAIT
MAS1
MAS, MGRA
MAS1 proto-oncogene, G protein-coupled receptor
GO Process (4)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ACE2
ACEH, UNQ868/PRO1885
angiotensin I converting enzyme 2
GO Process (15)
GO Function (8)
GO Component (6)
Gene Ontology Biological Process
- angiotensin catabolic process in blood [IC]
- angiotensin maturation [TAS]
- angiotensin-mediated drinking behavior [IMP]
- cellular protein metabolic process [TAS]
- positive regulation of reactive oxygen species metabolic process [IC]
- receptor biosynthetic process [IMP]
- receptor-mediated virion attachment to host cell [IDA]
- regulation of cell proliferation [TAS]
- regulation of cytokine production [IC]
- regulation of inflammatory response [IC]
- regulation of systemic arterial blood pressure by renin-angiotensin [IC, IMP]
- regulation of vasoconstriction [IC]
- regulation of vasodilation [IC]
- response to virus [IDA, IMP]
- viral entry into host cell [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
FRET
An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins.
Publication
Functional Complexes of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Receptors: Expression in Adult but Not Fetal Lung Tissue.
Angiotensin-converting enzyme 2 (ACE2) is a membrane peptidase and a component of the renin-angiotensin system (RAS) that has been found in cells of all organs, including the lungs. While ACE2 has been identified as the receptor for severe acute respiratory syndrome (SARS) coronaviruses, the mechanism underlying cell entry remains unknown. Human immunodeficiency virus infects target cells via CXC chemokine receptor ... [more]
Int J Mol Sci Dec. 16, 2020; 21(24); [Pubmed: 33339432]
Throughput
- Low Throughput
Additional Notes
- BRET
Curated By
- BioGRID