BAIT
CG1105
Dmel\CG1105, Dmel_CG1105
CG1105 gene product from transcript CG1105-RA
GO Process (0)
GO Function (0)
GO Component (0)
Drosophila melanogaster
PREY
EXO84
CG6095, DExo84, Dmel\CG6095, Exo84p, anon-WO0153538.55, onr, Dmel_CG6095
Exo84 ortholog (S. cerevisiae)
GO Process (14)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
- actomyosin contractile ring contraction [IMP]
- endocytic recycling [IMP]
- establishment or maintenance of cell polarity [IMP]
- maintenance of epithelial cell apical/basal polarity [IMP]
- meiosis I cytokinesis [IMP]
- meiosis II cytokinesis [IMP]
- meiotic spindle stabilization [IMP]
- neuron projection morphogenesis [IMP]
- neurotransmitter secretion [NAS]
- protein localization to plasma membrane [IMP]
- spermatid development [IMP]
- synaptic vesicle docking [NAS]
- synaptic vesicle targeting [NAS]
- vesicle-mediated transport [ISS]
Drosophila melanogaster
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Comparative interactome analysis of ?-arrestin families in human and Drosophila.
The ?-arrestins form a large family of evolutionally conserved modulators that control diverse signaling pathways, including both G-protein-coupled receptor (GPCR)-mediated and non-GPCR-mediated pathways, across eukaryotes. However, unlike ?-arrestins, only a few ?-arrestin targets and functions have been characterized. Here, using affinity purification and mass spectrometry, we constructed interactomes for 6 human and 12 Drosophila ?-arrestins. The resulting high-confidence interactomes comprised ... [more]
Elife Jan. 25, 2024; 12(); [Pubmed: 38270169]
Throughput
- High Throughput
Additional Notes
- Affinity capture MS was carried out to identify high confident protein interactors with a FDR of less than or equal to 0.01 and a minimum spectral count of 6
Curated By
- BioGRID