BAIT
CG10086
Dmel\CG10086, Dmel_CG10086
CG10086 gene product from transcript CG10086-RA
GO Process (0)
GO Function (0)
GO Component (0)
Drosophila melanogaster
PREY
LARP
0031/08, 0225/29, BcDNA:LD02611, CG14065, CG14066, CG42551, Dmel\CG42551, Dmel_CG14065, Dmel_CG14066, dlarp, l(3)S003108, l(3)S022529, larp1, Dmel_CG42551
La related protein
GO Process (9)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
- autophagic cell death [IEP]
- centrosome separation [IMP]
- male meiosis [IMP]
- mitochondrion inheritance [IMP]
- mitotic chromosome condensation [IMP]
- salivary gland cell autophagic cell death [IEP]
- spindle assembly [IMP]
- spindle assembly involved in male meiosis [IMP]
- syncytial blastoderm mitotic cell cycle [IMP]
Drosophila melanogaster
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Comparative interactome analysis of ?-arrestin families in human and Drosophila.
The ?-arrestins form a large family of evolutionally conserved modulators that control diverse signaling pathways, including both G-protein-coupled receptor (GPCR)-mediated and non-GPCR-mediated pathways, across eukaryotes. However, unlike ?-arrestins, only a few ?-arrestin targets and functions have been characterized. Here, using affinity purification and mass spectrometry, we constructed interactomes for 6 human and 12 Drosophila ?-arrestins. The resulting high-confidence interactomes comprised ... [more]
Elife Jan. 25, 2024; 12(); [Pubmed: 38270169]
Throughput
- High Throughput
Additional Notes
- Affinity capture MS was carried out to identify high confident protein interactors with a FDR of less than or equal to 0.01 and a minimum spectral count of 6
Curated By
- BioGRID