BAIT
CG43325
CG13514, CG30217, Dmel\CG43325, Dmel_CG30217, Dmel_CG43325
CG43325 gene product from transcript CG43325-RA
GO Process (0)
GO Function (0)
GO Component (0)
Drosophila melanogaster
PREY
DSX
CG11094, Dmdsx, Dmel\CG11094, Hr, ix-62c, Dmel_CG11094
doublesex
GO Process (32)
GO Function (8)
GO Component (1)
Gene Ontology Biological Process
- axon midline choice point recognition [IMP]
- central nervous system development [TAS]
- courtship behavior [NAS]
- female analia development [NAS]
- female sex differentiation [TAS]
- female somatic sex determination [NAS, TAS]
- genital disc development [IMP, TAS]
- genital disc morphogenesis [TAS]
- genital disc sexually dimorphic development [TAS]
- imaginal disc-derived female genitalia development [IGI, IMP, NAS]
- imaginal disc-derived male genitalia development [IGI, NAS]
- mRNA splicing, via spliceosome [TAS]
- male analia development [NAS]
- male courtship behavior [TAS]
- male courtship behavior, veined wing generated song production [NAS, TAS]
- male sex differentiation [TAS]
- male somatic sex determination [NAS]
- negative regulation of developmental pigmentation [TAS]
- negative regulation of transcription from RNA polymerase II promoter [TAS]
- negative regulation of transcription, DNA-templated [NAS]
- positive regulation of transcription from RNA polymerase II promoter [TAS]
- positive regulation of transcription, DNA-templated [NAS]
- regulation of imaginal disc growth [TAS]
- regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- regulation of transcription, DNA-templated [TAS]
- sex comb development [TAS]
- sex determination [NAS, TAS]
- sex differentiation [NAS, TAS]
- sex-specific pigmentation [NAS, TAS]
- somatic sex determination [NAS, TAS]
- spermatogenesis [NAS]
- transcription from RNA polymerase II promoter [NAS]
Gene Ontology Molecular Function- DNA binding [NAS, TAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- mRNA binding [NAS]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding transcription factor activity [ISS, NAS]
- zinc ion binding [NAS]
- DNA binding [NAS, TAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- mRNA binding [NAS]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding transcription factor activity [ISS, NAS]
- zinc ion binding [NAS]
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Next-generation large-scale binary protein interaction network for Drosophila melanogaster.
Generating reference maps of interactome networks illuminates genetic studies by providing a protein-centric approach to finding new components of existing pathways, complexes, and processes. We apply state-of-the-art methods to identify binary protein-protein interactions (PPIs) for Drosophila melanogaster. Four all-by-all yeast two-hybrid (Y2H) screens of?>?10,000 Drosophila proteins result in the 'FlyBi' dataset of 8723 PPIs among 2939 proteins. Testing subsets of ... [more]
Nat Commun Apr. 15, 2023; 14(1);2162 [Pubmed: 37061542]
Throughput
- High Throughput
Additional Notes
- interaction identified by large-scale Y2H screening and validated by pairwise testing
Curated By
- BioGRID