AP-2MU
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
TTK
Gene Ontology Biological Process
- R1/R6 development [IMP]
- R7 cell development [IMP, TAS]
- border follicle cell migration [IMP]
- brain morphogenesis [IMP]
- branch fusion, open tracheal system [IMP]
- branching involved in open tracheal system development [IMP]
- cell fate determination [TAS]
- chitin-based cuticle development [IMP]
- compound eye cone cell differentiation [IMP]
- compound eye corneal lens morphogenesis [IMP]
- dendrite morphogenesis [IMP]
- dorsal appendage formation [IMP]
- dorsal trunk growth, open tracheal system [IMP]
- imaginal disc-derived wing morphogenesis [IMP]
- inter-male aggressive behavior [IMP]
- locomotion involved in locomotory behavior [IMP]
- negative regulation of transcription from RNA polymerase II promoter [NAS]
- negative regulation of transcription, DNA-templated [IDA, IGI]
- neuron development [IMP]
- ovarian follicle cell development [IMP]
- peripheral nervous system development [TAS]
- positive regulation of DNA binding [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of cell shape [IMP]
- regulation of compound eye cone cell fate specification [IGI, IMP]
- regulation of embryonic cell shape [IMP]
- regulation of transcription from RNA polymerase II promoter [NAS]
- regulation of tube size, open tracheal system [IMP]
- startle response [IMP]
- tracheal outgrowth, open tracheal system [IMP]
Gene Ontology Molecular Function- DNA binding [IDA]
- POZ domain binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- chromatin binding [IDA]
- protein binding [IPI]
- protein homodimerization activity [IDA, IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
- DNA binding [IDA]
- POZ domain binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- chromatin binding [IDA]
- protein binding [IPI]
- protein homodimerization activity [IDA, IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Next-generation large-scale binary protein interaction network for Drosophila melanogaster.
Generating reference maps of interactome networks illuminates genetic studies by providing a protein-centric approach to finding new components of existing pathways, complexes, and processes. We apply state-of-the-art methods to identify binary protein-protein interactions (PPIs) for Drosophila melanogaster. Four all-by-all yeast two-hybrid (Y2H) screens of?>?10,000 Drosophila proteins result in the 'FlyBi' dataset of 8723 PPIs among 2939 proteins. Testing subsets of ... [more]
Throughput
- High Throughput
Additional Notes
- interaction identified by large-scale Y2H screening and validated by pairwise testing
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| TTK AP-2MU | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID