BAIT

TOM20

CG7654, Dmel\CG7654, TOM 20, anon-WO0118547.225, dtom20, Dmel_CG7654
Translocase of outer membrane 20
GO Process (1)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Drosophila melanogaster
PREY

COPROX

BcDNA:GM14838, CG3433, Dmel\CG3433, l(2)k10617, l(2)k11018, Dmel_CG3433
Coproporphyrinogen oxidase
GO Process (1)
GO Function (2)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Drosophila melanogaster

Proximity Label-MS

An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.

Publication

In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary.

Nguyen TTM, Munkhzul C, Kim J, Kyoung Y, Vianney M, Shin S, Ju S, Pham-Bui HA, Kim J, Kim JS, Lee M

PIWI-interacting RNAs (piRNAs) are small RNAs that play a conserved role in genome defense. The piRNA processing pathway is dependent on the sequestration of RNA precursors and protein factors in specific subcellular compartments. Therefore, a highly resolved spatial proteomics approach can help identify the local interactions and elucidate the unknown aspects of piRNA biogenesis. Herein, we performed TurboID proximity labeling ... [more]

Development Feb. 15, 2023; 150(4); [Pubmed: 36762624]

Throughput

  • High Throughput

Additional Notes

  • Proximity Label MS was carried out to identify high confidence germline cell protein interactors with >2 fold change over control and q-value<0.05

Curated By

  • BioGRID