BAIT
CRY
CG3772, DCry, Dm-CRY1, DmCRY, DmCRY1, Dmel\CG3772, anon-WO0140519.17, anon-WO0140519.19, anon-WO0140519.20, anon-WO0172774.15, cryb, Dmel_CG3772
cryptochrome
GO Process (17)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- UV-A, blue light phototransduction [ISS]
- blue light signaling pathway [IMP]
- circadian rhythm [IEP, IGI, IMP, IPI, NAS, TAS]
- detection of light stimulus involved in magnetoreception [IMP]
- entrainment of circadian clock [IDA, IMP]
- entrainment of circadian clock by photoperiod [IGI, IMP]
- gravitaxis [IMP]
- locomotor rhythm [IMP]
- magnetoreception [IMP]
- negative regulation of transcription, DNA-templated [IMP]
- phototransduction [IMP]
- protein import into nucleus, translocation [IMP]
- regulation of circadian rhythm [IDA, IMP]
- regulation of circadian sleep/wake cycle, sleep [IMP]
- response to blue light [NAS, TAS]
- response to light stimulus [IMP, TAS]
- response to magnetism [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
PEP
CG6143, Dmel\CG6143, PEP/X4, X4/PEP, p100, Dmel_CG6143
Protein on ecdysone puffs
GO Process (2)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Interactions of drosophila cryptochrome.
In this study, we investigate the intricate regulatory mechanisms underlying the circadian clock in Drosophila, focusing on the light-induced conformational changes in the cryptochrome (DmCry). Upon light exposure, DmCry undergoes conformational changes that prompt its binding to Timeless and Jetlag proteins, initiating a cascade crucial for the starting of a new circadian cycle. DmCry is subsequently degraded, contributing to the ... [more]
Photochem Photobiol Feb. 05, 2024; (); [Pubmed: 38314442]
Throughput
- High Throughput
Additional Notes
- (APEX2) Proximity Label MS was carried out to identify high confidence protein interactors in light conditions
Curated By
- BioGRID