BAIT

ME31B

CG4916, DDX6, Dhh1p/Me31b, DmRH3, Dmel\CG4916, Mat31B, l(2)k06607, Dmel_CG4916
maternal expression at 31B
Drosophila melanogaster
PREY

PMP70

CG12703, Dmel\CG12703, i17, Dmel_CG12703
CG12703 gene product from transcript CG12703-RD
GO Process (1)
GO Function (2)
GO Component (3)
Drosophila melanogaster

Proximity Label-MS

An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.

Publication

In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor.

Baker FC, Neiswender H, Veeranan-Karmegam R, Gonsalvez GB

Numerous motors of the Kinesin family contribute to plus-end-directed microtubule transport. However, almost all transport towards the minus-end of microtubules involves Dynein. Understanding the mechanism by which Dynein transports this vast diversity of cargo is the focus of intense research. In selected cases, adaptors that link a particular cargo with Dynein have been identified. However, the sheer diversity of cargo ... [more]

Development Dec. 15, 2020; 148(22); [Pubmed: 35020877]

Throughput

  • High Throughput

Curated By

  • BioGRID